Adrenaline (Epinephrine), Urine (24-Hour Test)

What it is:
This test measures the amount of adrenaline (epinephrine), a hormone and neurotransmitter produced by the adrenal glands, in a 24-hour urine sample. Adrenaline helps regulate the body’s “fight or flight” response, affecting heart rate, blood pressure, and metabolism.

Uses

• Detect and monitor adrenal tumors such as pheochromocytoma or paraganglioma

• Investigate causes of hypertension (high blood pressure)

• Evaluate symptoms suggestive of excess adrenaline production

Symptoms That May Lead to the Test

• Persistent or episodic high blood pressure

• Severe headaches

• Sweating episodes

• Rapid or irregular heartbeat (palpitations)

• Anxiety, tremors, or panic-like episodes

Abnormal Results

• High adrenaline levels:

  • Pheochromocytoma or paraganglioma

  • Severe stress or anxiety

  • Certain medications or stimulant use

  • Hypoglycemia

  • Acute illness or trauma

• Low/normal levels:

  • Expected in healthy individuals

  • Not usually clinically significant on its own

Risks

• No direct risks; requires only a 24-hour urine collection (inconvenient but non-invasive).